Posted by AndrewB on February 19, 2001, at 11:21:14
If you are a smoker and ADD or bipolar disorder you may wish to ask your doctor about a trial with mecamylamine (Inversine). For smoking cessation, when combined with the nicotine patch it seems to be much more effective than the patch alone. There a couple of case reports of people with combined tourettes syndrome and bipolar who were stabilized with mecamylamine (it took away the mood swings and improved anxiety and concentration). Also supposedly some doctors have had success with it in treating ADD. This is very slim evidence but I thought that the option of trying mecamylamine might be considered since it reportedly has almost no side effects (mild constipation) at the low doses in which it is used. Seemingly it may take 3 weeks or longer to be effective for bipolar, while onset of action is within hours for ADD.
References below:
www.laytonbio.com/inversine/bipolar.pdf.
www.update-software.com/ccweb/cochrane/revabstr/ab001009.htm.
http://216.247.218.98/morehealth/8555.html.For more information refer to the article “Clinical Relevance of the Nicotine Receptor Antagonist Mecamylamine in Treating Neuropsychiatric Disorders.” Todays Therepeutic Trends. 18(3): pp.255-73, 2000.
AndrewB
poster:AndrewB
thread:54389
URL: http://www.dr-bob.org/babble/20010212/msgs/54389.html