Posted by kate9999 on February 26, 2001, at 4:45:34
In reply to nardil, posted by wynn on February 25, 2001, at 17:35:17
There are smarter people to answer this, but I'll start throwing some ideas out.
I'd be thinking Lithium or Thyroid. These are both commonly used relatively effective augmenting agents. I know lithium can be added to an MAOI. And I'm pretty sure thyroid can, but since I'm not a walking PDR I'll hedge and say look it up to find out for sure.
There are other augmenters too - e.g. I took Neurontin with Nardil and it helped a lot (though I had to dump it recently because of hypertension). I'm sure other people can give you lots of other ideas.
I'd say adding other antidepressants is OUT. Especially given the fact that there aren't first rate psychopharmacologists in your area. SSRI's (Prozac, Zoloft, etc.) are ALWAYS out with MAOIs, as are other MAOIS. Tricyclics are risky - but some say some do it (I've never known anybody that has). I don't know about the novel antidepressants (eg. Wellbutrin, Effexor) but I'd expect they're at least as risky as tricylics and maybe as risky as SSRI's.
Also, if he's had some good effects with Nardil, he could try switching to Parnate, which is another MAOI. And if he's not tried cognitive behavioral therapy he should. Exercise also has an antidepressant effect.
There's also the issue of time. If he's had some effect, and he's not at the maximum dosage he should go there and stay there for at least a month, see what happens.
> I have a friend who is taking Nardil and is almost up to the maximim dosage. For most patients Nardil is sufficient to provide relief, but for him it is not enough. He asked me to try to find out if there are any possible drugs that could be taken with Nardil to enhance its effects. He is having difficulty finding anyone in our town who has expert knowledge about this. If you have any suggestions at all about antidepressants that could be helpful if taken in combination with Nardil, your comments would be most helpful. Thanks.
poster:kate9999
thread:54817
URL: http://www.dr-bob.org/babble/20010221/msgs/54853.html