Posted by Eric on March 7, 2001, at 10:48:59
In reply to Prozac Zyprexa Study, posted by Neal on March 6, 2001, at 1:06:13
> A Vanderbilt study has found that Prozac and the antipsychotic Zyprexa work better together on treatment-resistant depression patients than either drug alone. Twenty-eight patients were given either Prozac and a placebo, Zyprexa and a placebo, or the two drugs together. After eight weeks, researchers found a "minimal" improvement with Prozac, a "modest" improvement with Zyprexa, and a "significant" improvement with the combination.
What else would you expect them to say though? Both drugs are made by Eli Lilly and obviously Eli Lilly wants to sell as much of both meds as possible. This study was sponsored by Eli Lilly.Instead, what Eli Lilly should be really doing is trying to R & D new psychiatry meds specifically for treatment resistant depression and for psychotic depression. Because there is a percentage of treatment resistant patients who have major trouble combining psych medications...some people just cannot do that.
Actually Seroquel is a superior neuroleptic augmentor compared to Zyprexa in many cases because Seroquel does not use the 2D6 liver enzyme for drug metabolism.
Seroquel is least likely to cause pharmacokinetic drug interactions when combined with antidepressants. It also causes less weight gain compared to Zyprexa.
poster:Eric
thread:55673
URL: http://www.dr-bob.org/babble/20010302/msgs/55840.html