Posted by steve on March 15, 2001, at 14:06:55
In reply to Re: Selegilene Transdermal Patch, posted by Lorraine on March 15, 2001, at 9:54:17
> S. : I'm not taking Selegiline for its bedtime performance. I'm taking it because it is a selective MAO inhibitor, meaning I get the benefits of an MAO inhibitor without the dietary restrictions. Selegiline actually is a neuroprotective and neurorestorative agent. So I'm feeling lucky as long as I can stay on it. It extends the life of rats. It is not like cocaine, although it metabolizes into methamphetamine, the belief is that that is not its main mode of action. No doubt though that it is a puppy upper. Do a search on Medline if you want some info about it. It is a very interesting drug.
You wouldn't happen to have references for it's being a neuroprotective and expanding longetivity would you?
I've heard the same thing, but on the other hand, I've also heard McEwen, the designer of tianeptine report that tianeptine is a neuroprotective in the hippocampus due to its acceleration of 5ht reuptake. Now to me it seems that either slowing or accelerating 5ht reuptake will avoid cell death, but I don't see how both will. I also notice how commericial interests are much more likely to report the "neuroprotective" effects of what they are peddling than any (significant) neurotoxicity. So which is it?
S.
poster:steve
thread:56167
URL: http://www.dr-bob.org/babble/20010310/msgs/56588.html