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Re: provigil. . . adrafinil?

Posted by JohnL on April 15, 2001, at 4:27:51

In reply to Re: provigil. . . adrafinil? » JohnL, posted by jacquie on April 14, 2001, at 21:37:27

Jacquie,
I don't see any problem combining Wellbutrin+Adrafinil. You'll just have to sample it and see. I would think if it overdoes it then you may get an excess norepinephrine type headache or maybe experience some anxiety.

I have combined Adrafinil with all kinds of meds, but it seems to go especially well with Prozac, Zyprexa, or both. Like you I experienced a rather quick poopout when I took Adrafinil by itself. But with Prozac and/or Zyprexa it works great all the time. Not sure why. But I don't argue with results. For whatever reason, these drugs work for me.
John

> JohnL
>
> Would you combine Wellbutrin and Adrafinil together
> or is that over doing it? I take Wellbutrin. I have
> tried adranfinil, but found it effective in the first week,
> but then it somehow seemed to fade away. Any thoughts??
> jacquie
>
>
> > Cole,
> > Just my experience, but Adrafinil is so much better than Provigil I can't find the words to tell you.
> >
> > I had the EXACT same response to Provigil as you. Spaced out, easily exhausted, overall yuck. And oh my, what a price tag indeed! And like you, I also had the same reaction to Wellbutrin. So you and I could apparently be on the same page.
> >
> > I certainly can't predict what the best thing to do is. But I can say, in your shoes, I would for myself order some Adrafinil today, stop Provigil today, start taking Adrafinil in about a week when you get it, and look for a good response from 2 to 4 weeks after that. All I can say is, it isn't anything like Provigil. Just the opposite. And the $25 price tag is nice. It amazes me how something so cheap and so mild can work so good. I don't understand that. Nevertheless, it works great, and that's all I care about. The cheap price is icing on the cake.
> >
> > Like you, I also take Remeron, though my dose is much lower than yours. So I can verify from months of personal experience that Remeron and Adrafinil do go together rather nicely. This may be especially interesting since you and I seem similar in a lot of ways. If you try Adrafinil, don't expect immediate results. You may not feel anything for a week or two. I doubt seriously you'll feel any of the yuckiness you did with Provigil. And if you're like me, just one tab a day is all it will take for increased energy, motivation, renewed vitality, and improved cognition. It is strange though how these effects come on gradually over several weeks.
> >
> > Someone mentioned concern over liver enzymes with Adrafinil, in another post. I forgot to address that. Hopefully they'll read this. The liver enzyme situation is rather rare, but occurs primarily at higher doses (3 to 4 tabs a day) for extended periods of time (months or years). Low doses like 1 or 2 tabs a day are not likely to be much of a risk. Regardless, it's always a wise move to have a liver test once or twice a year anyway while taking ANY psychiatric medication, not just Adrafinil. After six months with Adrafinil at one tab per day, my liver test came back looking the same as before I started.
> > John


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