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Re: Prozac and Zyprexa combination

Posted by loosmrbls on May 15, 2001, at 11:06:42

In reply to Prozac and Zyprexa combination, posted by Sergios on May 15, 2001, at 10:47:32

I have a few questions:

1) Why the switch from one SSRI to another, in this case Paxil to Prozac?
2) How much Paxil were you on?
3) Since you are on Zyprexa as well, what diagnosis are you being treated for?

Paxil is one of the shortest half-life SSRI's out there, and it probably cleared your system pretty quickly and by now, a month later, should be completely gone. So I think some residual Paxil effect is unlikely.

Prozac can take as long as 4-6 weeks to reach steady states. I might give it another week at the most, but I don't know why pdocs expect these overnight miracles. If you haven't had any improvement after a month of Prozac, I wouldn't expect more than a partial response (based on my own drug experiences).

These symptoms you describe sound somewhat hypomanic or even mixed in nature.

But to answer your question based on the info, I would give it maybe another week. If no improvement, I don't see what waiting another two weeks will do.


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poster:loosmrbls thread:63084
URL: http://www.dr-bob.org/babble/20010515/msgs/63090.html