Posted by SalArmy4me on May 17, 2001, at 0:01:34
In reply to meds and white blood cell count, posted by cellocarly on May 16, 2001, at 20:51:35
I searched through the literature and found that most references to altered-WBC count in psychiatry were of persons treated with 1) clozapine, or 2) lithium + risperidone. Only one report suggested that a conventional antidepressant may alter WBC counts _significantly_.
Freeman, Marlene P. MD. Stoll, Andrew L. MD. Mood Stabilizer Combinations: A Review of Safety and Efficacy. Am J Psychiatry. 155(1):12-21, January 1998.
"In contrast to the relative safety observed by Tohen et al. [72], cases of fever, high creatine phosphokinase levels and WBC counts, and delirium have been reported by others [74,75]. Therefore, caution should be exercised when using lithium and risperidone in combination."Swanson, Charlie L. Jr.. Price, William A.. McEvoy, Joseph P.. Effects of Concomitant Risperidone and Lithium Treatment. American Journal of Psychiatry. 152(7):1096, July 1995.
Also: FINKEL, BORIS MD. LERNER, ARTURO G. MD. OYFFE, IGOR MD, PHD. SIGAL, MIRCEA MD. Risperidone-Associated Agranulocytosis. American Journal of Psychiatry. 155(6):855-856, June 1998.
Vallone, Doris C. MSN, RN, C. Pharmacology in Practice: Antidepressants and anxiolytics. RN. 60(7):27-33, July 1997 -- "Bupropion may cause seizures, and drinking alcohol can increase that risk... Also keep in mind that certain diagnostic and lab test results may be affected in patients taking this drug. You may see premature beats and nonspecific ST changes on a patient's EKG. White Blood Cell count may also drop by up to 14%."
poster:SalArmy4me
thread:63290
URL: http://www.dr-bob.org/babble/20010515/msgs/63307.html