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Re: Moban (molindone) for depression? EPS? » SLS

Posted by SalArmy4me on May 18, 2001, at 22:34:49

In reply to Moban (molindone) for depression? EPS?, posted by SLS on May 18, 2001, at 21:07:23

I speculate that Molindone has an antidepressant effect because of its greater affinity for 5HT1a receptors than clozapine. I'm not sure about the EPS part, but I think it will be good for you to know that you have less of a chance of gaining weight on molindone:

Allison DB et al. Antipsychotic-induced weight gain: a comprehensive research synthesis. Am J Psychiatry 1999; 156:1686-1696:
"This is the most comprehensive meta-analysis of weight gain associated with different antipsychotic agents conducted to date, and allows for a comparison among various old and new agents. Clozapine and olanzapine are associated with greatest weight gain, and molindone and ziprasidone are associated with the least."


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URL: http://www.dr-bob.org/babble/20010515/msgs/63565.html