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Synthroid study » SalArmy4me

Posted by Jane D on June 3, 2001, at 0:45:48

In reply to Synthroid » lissy, posted by SalArmy4me on June 2, 2001, at 23:22:11

> Dong, Betty J. et al. "Bioequivalence of Generic and Brand-name Levothyroxine Products in the Treatment of Hypothyroidism" JAMA. 277(15):1205-1213, April 16, 1997:
>
...
> "The 4 generic and brand-name levothyroxine preparations studied are different but are bioequivalent by current FDA criteria and are interchangeable in the majority of patients receiving thyroxine replacement therapy."
> JAMA.1997

Sal,

This doesn't address the problem of inconsistent quality. All it says is that at 1 point in time the different versions were equivalent.

By the way, do you know that you are citing a notorious study. It was financed by Synthroid's maker to show that Synthroid was better. When it didn't they blocked publication for years. There's a free full text account in the BMJ (and in dozens of other places).
For the BMJ: Go to www.bmj.com
Select Search/Archive, and in the box labeled "Search by Citation" put in Volume 314, Page 1145.

It's interesting.

Jane


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