Posted by DebbieLynn on June 29, 2001, at 17:58:34
In reply to Re: Serotonin Syndrome, posted by SalArmy4me on June 29, 2001, at 12:14:26
> I ran that through a drug checker and they said that serotonin syndrome from that combination is possible, but highly rare:
>
> Effexor XR has a "major" interaction with Prozac:
> "The combining of agents that can inhibit serotonin reuptake and/or other agents with serotonergic activity (including some medications for migraine therapy and certain opioids) may potentiate the risk of serotonin syndrome, which is a rare but serious and potentially fatal condition thought to result from hyperstimulation of brainstem 5HT1A receptors. In general, the concomitant use of multiple serotonergic agents should be avoided if possible, or otherwise approached with caution if potential benefit is deemed to outweigh the risk. Close monitoring is recommended for signs and symptoms of excessive serotonergic activity such as CNS irritability, altered consciousness, confusion, myoclonus, ataxia, abdominal cramping, hyperpyrexia, shivering, pupillary dilation, diaphoresis, hypertension, and tachycardia..."
>
What about 225mg of Effexor XR and 20mg of Celexa?? Any risk of serotonin syndrom? I have been at these doses for 4 days. Actually, I feel pretty good.
Debbie
poster:DebbieLynn
thread:68342
URL: http://www.dr-bob.org/babble/20010625/msgs/68383.html