Posted by sl on July 10, 2001, at 14:34:23
In reply to Re: Nortriptyline, Prozac, Wellbutrin....SR? » sl, posted by SalArmy4me on July 10, 2001, at 13:30:13
Yeah, I saw that too. I believe it IS clinically relevant, cuz I am experiencing serious sedation.But anyway, so I should be able to take Wellbutrin in the morning WHILE tapering off Nortrip. That's good to know. :)
sl
> I ran the combo through a drug checker, but keep in mind that the drug checker at www.drkoop.com is very reactionary--it comes up with stuff that may not be clinically relevant:
>
> 1. Severe Interaction between Pamelor (generic: nortriptyline) and Prozac (generic: fluoxetine)
>
> Marked increases in plasma tricyclic antidepressant levels have been reported after administration of fluoxetine. Seizures and delirium have been reported. The mechanism is likely related to fluoxetine-induced inhibition of the cytochrome P450 system. Caution and close observation for evidence of tricyclic toxicity are recommended if these drugs must be used together.
poster:sl
thread:69596
URL: http://www.dr-bob.org/babble/20010708/msgs/69627.html