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Re: How LONG should one try med for (ATTN:pellmell) » Janelle

Posted by SalArmy4me on July 11, 2001, at 21:00:21

In reply to How LONG should one try med for (ATTN:pellmell), posted by Janelle on July 11, 2001, at 20:32:23

http://www.vh.org/Providers/Conferences/CPS/11.html

A more recent placebo-controlled study by Quitkin et al (1996) reported on 693 patients treated prospectively with a variety of antidepressant regimens. A response criterion was a sustained score on the CGI of much improved or very much improved. All patients were rated weekly. They concluded that those patients with some improvement in depressive signs/symptoms by week 4 should have their antidepressant regimen continued until week 6. This was based on the observation that 39% (versus 8% of placebo) of patients at week 4 that had minimal improvement were responders at week 6. However, if at week 4 the patient has had no improvement, then the treatment should be changed. This was based on the observation that for drug and placebo only 13% and 6%, respectively went on to respond at week 6.


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poster:SalArmy4me thread:69796
URL: http://www.dr-bob.org/babble/20010708/msgs/69799.html