Posted by SalArmy4me on July 11, 2001, at 22:18:06
In reply to Help! Need reactions to LUVOX for anxiety, OCD!, posted by Janelle on July 11, 2001, at 15:34:11
Here is the latest study on Luvox for anxiety, albeit with children:
Walkup, John T.. Labellarte, Michael J.. Riddle, Mark A.. Pine, Daniel S.. Greenhill, Laurence. Klein, Rachel. Davies, Mark. Sweeney, Michael. Abikoff, Howard et al. Fluvoxamine for the Treatment of Anxiety Disorders in Children and Adolescents. New England Journal of Medicine. 344(17):1279-1285, April 26, 2001:
Our report demonstrates the efficacy of fluvoxamine in the treatment of children with social phobia, separation anxiety disorder, or generalized anxiety disorder. Fluvoxamine treatment was generally well tolerated but was associated with significantly more gastrointestinal symptoms, as found in other trials, [6,7,13-17] and with greater increases in children's levels of activity than was placebo. Effects on activity have been found in previous trials of selective serotonin-reuptake inhibitors in children, particularly in children younger than 13 years of age, [7] but such effects typically have not been found in adults. [12-14] This increase in activity in children may relate to subjective effects in adults taking these drugs, who sometimes report increases in energy. Regardless of the mechanism, the side effects in the fluvoxamine group were usually mild. Only 5 of the 63 children in the fluvoxamine group discontinued treatment as a result of adverse events, as compared with 1 of the 65 children in the placebo group.
The efficacy of treatment with selective serotonin-reuptake inhibitors for anxiety in children in our trial is consistent with data obtained in studies of adults. Panic disorder, social phobia, and obsessive-compulsive disorder are the three specific anxiety disorders in adults whose treatment with these drugs has been studied most intensively. [12-15] In general, approximately 50 to 70 percent of patients with these disorders respond to therapy with selective serotonin-reuptake inhibitors; response rates in patients with panic disorder are usually higher than in patients with the other disorders. The results of our trial in children with social phobia, separation anxiety disorder, and generalized anxiety disorder are also consistent with the results of trials of these drugs in children with obsessive-compulsive disorder and major depression. [6,7,16,17,26]
poster:SalArmy4me
thread:69748
URL: http://www.dr-bob.org/babble/20010708/msgs/69803.html