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Re: stimulant tolerance - help

Posted by Andy123 on July 14, 2001, at 7:24:15

In reply to Re: stimulant tolerance - help » Andy123, posted by Grouch on July 13, 2001, at 21:20:33

> Andy,
> Just curious... where did you get the idea to use phosphatidyl serine for stimulant tolerance, and can you explain pharmacologically how it may work?
> Also, how do the antioxidants interact with stimulants. I've heard that taking vitamin C with adderall is actually a BAD idea (reduces absorption).

Hi Grouchie,
Yes, vitamin C taken before amphetamine does reduce drug absorption. I take it at night.
Concerning the phosphatidylserine:
Klinkhammer, P. Szelies B and Heiss WD. "Effect of phosphatidylserine vs. placebo in patients with early dementia of the Alzheimer type." Eur. Neuropsychopharmacol. Vol.2, #2, pg. 149-155. (this is a dutch publication I haven't read myself, but its results are desribed in Ward's "Smart Drugs II."
The article suggests that phosphatidylserine increases receptor expression, among other activities.
Concerning the anti-oxidants: I'll get back to you on this :) It could very well be that this is just wishful thinking. My intuition tells me its worthwhile though.


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