Posted by SalArmy4me on July 28, 2001, at 22:10:01
In reply to effexor about to be stopped.*PLEASE READ*, posted by Stef on July 28, 2001, at 18:57:53
More scientific studies have been done on the role of Fluoxetine in Anger Episodes, so I'll present that first... Prozac might provide relief from sedation also, as most people find it stimulating:
1) Salzman, Carl MD. Effect of Fluoxetine on Anger in Symptomatic Volunteers With Borderline Personality Disorder. Journal of Clinical Psychopharmacology. 15(1):23-29, February 1995.
2) Fava, M. Anger Attacks in Unipolar Depression, Part 1: Clinical Correlates and Response to Fluoxetine Treatment. Year Book of Psychiatry & Applied Mental Health. 1995(10):463-464, Annual 1995:"Anger attacks were reported at baseline by 44% of patients. Compared with patients without anger attacks, these patients had significantly higher scores for anxiety, somatization, and state and trait hostility. All of these scores decreased significantly after fluoxetine treatment, and the attacks disappeared in 71% of treated patients. Patients with anger attacks had a somewhat greater degree of overall clinical improvement than those without attacks..."
Other ideas: Nefazodone
Domon, Steven E. M.D.. Andersen, Mark S. M.D.. NEFAZODONE FOR PTSD. Journal of the American Academy of Child & Adolescent Psychiatry. 39(8):942-943, August 2000:
"We have found that nefazodone may be particularly useful in addressing the symptoms... These include improvements not only in anger and aggression, but in restlessness, insomnia, and even concentration. In the context of residential treatment we have observed an improvement in avoidance, anhedonia, and detachment. Our patients often report an improvement in both sleep duration and quality. Improvement in sleep and the symptoms of hyperarousal are consistent with those changes observed in adult patients..."
Valproate:Davis, Lori L. MD. Comprehensive Review of the Psychiatric Uses of Valproate. Journal of Clinical Psychopharmacology. 20(1) Supplement 1:1S-17S, February 2000:
"Four of the eight completers were rated as responders for overall pathology, four were responders on scores for mood, and three were responders on scores for anxiety, ANGER, impulsivity, and rejection sensitivity. There was a significant decrease in the self-rated Symptom Checklist-90. The total score on the Overt Aggression Scale decreased, but not significantly. There was a significant decrease in global subjective irritability. Thus, treatment with VPA (Valproic Acid) in combination with psychotherapy led to overall improvement in 50% of the patients who completed the 8-week trial."
Helpful Links:
http://www.dr-bob.org/tips/split/Fluoxetine-for-irritabilit.html
http://www.dr-bob.org/tips/split/Mood-stab-stim-for-anger.html
poster:SalArmy4me
thread:72262
URL: http://www.dr-bob.org/babble/20010725/msgs/72291.html