Posted by Mitch on August 10, 2001, at 23:22:58
In reply to Re: OK, am I just a freak? (long) » Mitch, posted by MB on August 10, 2001, at 16:40:25
> Maybe it's more sedating at those lower doses because you're not getting the noradrenergic stimulation? I've been told that if you up the dose with Remeron to 45mg, it's less sedating. I've always been WAY to nervous to try it. I get scared it won't work and I'll become Rip Van Winkle < g >.MB,
Yes they are correct about higher doses being *somewhat* less sedating. I started out with 7.5mg at bedtime and then increased it to 15mg and then 30mg. It was like "still taking 100mg of Benadryl at nite minus the cottonmouth" but with a boosted norepinephrine effect the next day to *overcome* the sedation. Basically, the way I felt with it was that 7.5mg caused the SAME sedation as 30mg did, you just had more stimulant effect to *offset* the drowsiness. The "next-day fog" though seemed to blurr my cognition so badly (no matter what dose I took)that I had problems with work. I have a very high-tech detaily job and anything that disrupts my thinking just WRECKS my ability to do my job. The *NE boost* just wasn't quite enough, sorry Charlie. Hey, if they could find a way to hit the 5-HT and NE receptors without the antihistamine thing I would probably find it an AD of choice. It was one of only a few AD's that I can take a standard dose of-so that in itself is a pretty good deal.
Mitch
poster:Mitch
thread:74429
URL: http://www.dr-bob.org/babble/20010809/msgs/74565.html