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Re: (SalArmy4me)Taking combination of drugs ok? » Storm

Posted by SalArmy4me on August 29, 2001, at 19:16:26

In reply to Re: (SalArmy4me)Taking combination of drugs ok?, posted by Storm on August 29, 2001, at 19:04:05

A reaction between Prozac and Remeron is possible and has been noted once in the literature:

Benazzi F. Serotonin syndrome with mirtazapine-fluoxetine combination. International Journal of Geriatric Psychiatry. 13(7):495-6, 1998 Jul.

But I myself have not seen a bad drug-drug interaction between the two in clinical practice... Generally there is a low incidence of interactions between an SSRI and mirtazapine:

Holm KJ. Markham A. Mirtazapine: a review of its use in major depression. Drugs. 57(4):607-31, 1999 Apr:

"The low potential for interaction with drugs that are metabolised by CYP2D6, including antipsychotics, tricyclic antidepressants and some SSRIs, may also make mirtazapine an important option for the treatment of major depression in patients who require polytherapy..."

Bottom-line in this case: Do what your physician tells you to do.


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