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Re: Really different!! » Cruz

Posted by SLS on September 6, 2001, at 22:32:03

In reply to Really different!!, posted by Cruz on September 6, 2001, at 14:36:11

>
> I am currently trying Ketoconazole, which so far has been great! The theory is that it lowers cortisol which most of us produce to much of. A theory is just a theory and the proof of the pudding is in the tasting. I am experimenting now to see how little Ketoconazole I need to take. My circadian rythmn is key to my condition I think. Its like I have jet lag and not depression per se.
> I wish I understood my condition, but the understanding of mood didorders has more unknowns than knowns. Well you asked for something different and thats were I'm at. Good luck!


Hi.

Drug companies have been working feverishly to develop CRH antagonists to treat depression. These drugs reduce cortisol production and are supposed to have a better side-effect profile than does ketoconazol.

I had been playing around with the idea of trying ketoconazol a few years ago. Maybe I'll put it on my short list.

How much are you taking? How long did it take to work? In what ways has it made you feel different? Are you taking anything else?

Thanks in advance. I am so glad to hear that things are working out for you.

Here's a nice little piece describing the involvement of the LHPA and cortisol in depression.

LHPA = Limbic Hypothalamo-Pituitary Axis

http://www.thedoctorwillseeyounow.com/articles/behavior/depressn_5/

- Scott

 

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