Posted by Elizabeth on September 12, 2001, at 5:37:06
In reply to Re: DXM in Ecstasy » fachad, posted by Cam W. on September 8, 2001, at 18:22:42
> Fachad - Actually guaifenecine is the active ingredient in Robitussin™ and dextromethorphan is an active component of Robitussin DM™.
Actually, Robitussin DM has multiple active (?) ingredients. Robitussin Maximum Strength contains only DXM, no other actives.
Interestingly (to me, anyway), DXM appears to slow the development of tolerance to morphine.
> It does seem to have nocieceptive activity, in some people; but researchers say that, because of the psychotomimetic side effects, it should not be used as a first line agent.
AFAIK, it does not have any "psychotomimetic" effects. "Psychotomimetic" is a word that's been misused a lot to describe hallucinogenic or psychedelic drugs. I think the appropriate term for drugs like DXM and ketamine would be "dissociative."
Jason: could you provide some references about the putative MAOI activity of DXM? TIA. To my knowledge, reactions with MAOIs are quite possible (though not as serious as, say, with Demerol), but interactions with SSRIs are relatively rare. (I'd still avoid it with SSRIs, especially if you're using it in recreational doses.)
-elizabeth
poster:Elizabeth
thread:78291
URL: http://www.dr-bob.org/babble/20010907/msgs/78637.html