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Re: Experiences w/ switching from SSRI to tricyclic? » lisamb

Posted by SalArmy4me on September 20, 2001, at 10:45:08

In reply to Experiences w/ switching from SSRI to tricyclic?, posted by lisamb on September 20, 2001, at 4:46:41

Desipramine has less side-effects and has been studied more for ADD than imipramine.

Wilens, Timothy E. MD et al. Six-Week, Double-Blind, Placebo-Controlled Study of Desipramine for Adult Attention Deficit Hyperactivity Disorder. American Journal of Psychiatry. 153(9):1147-1153, September 1996:

"...The magnitude of the reduction in ADHD symptoms with desipramine is similar to that reported in adults with ADHD who received robust doses of methylphenidate. Like methylphenidate, desipramine treatment resulted in significant reductions in the broad categories of inattention, impulsivity, and hyperactivity. The current findings with desipramine, together with previously reported findings with psychostimulants, support the notion that pharmacological agents effective in reducing ADHD symptoms appear to operate through their catecholaminergic properties..."


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URL: http://www.dr-bob.org/babble/20010917/msgs/79151.html