Posted by Sparkboy on October 4, 2001, at 0:26:44
In reply to Amisulpride at Low Doses, posted by SalArmy4me on October 2, 2001, at 15:42:30
> Why is it said that Amisulpride works better for depressed states at 50-100 mg? Wouldn't more be better (300-600 mg)?
At low doses, amisulpride has a preference for pre-synaptic receptors (auto-receptors). Blocking these, the theory goes, tricks a feedback loop into increasing dopamine release into the synapse.
The higher dose also blocks post-synaptic receptors (conventional anti-psychotic).
poster:Sparkboy
thread:80066
URL: http://www.dr-bob.org/babble/20010927/msgs/80227.html