Posted by MB on October 22, 2001, at 16:53:41
In reply to medication poop-out questionaire, posted by JohnX on October 21, 2001, at 16:32:01
OK, first off, let me say that all the SSRIs (except Prozac) made me feel 75% better within a few hours. Paxil actually made me feel on top of the world after a single dose. Then, after a period of a few days, the "up" feeling goes away, and I just feel sick: irritable, sweaty, can't sleep very well (toss and turn), restless legs, etc. This lasts about two months, and then the the side effects shift. At the 8 week mark, I become fatigued, tired *all the time*, can't wake up in the morning, can't quit eating sweets, and the weight starts piling on. I have to say that the great mood induced by the first dose NEVER returns. So, contrary to what the literature predicts, I don't feel maximum relief after 8 weeks. I feel maximum relief for the first few days; then anxious, irritable hell for eight weeks; and then I become a zombie with no emotions or motivation or anything. It's totally weird since most people get poop-out after years (or months).
Has anybody else noticed that when they withdraw from an antidepressant and then start up again it's like a totally different drug (e.g., different side effects or more/less tolerable)? Now, when I try an SSRI, I go straight to the anxiety/rage/irritible stage. Is this a kindling thing? I mean, can lots of starts and stops kindle a latent bipolar issue?
> A few people on this newsgroup including myself
> and SLS have posted issues with getting medication
> responses that quickly "poop out".
>
> I was wondering if I could put a feeler out for
> those who have had this issue. I would be interested
> in knowing on what meds this happened and how it
> occured, and in particular if this has been an issue
> with quick acting meds like Adderall, Dexedrine,
> Provigil, and Cylert.
>
> Thanks,
> John
poster:MB
thread:81909
URL: http://www.dr-bob.org/babble/20011015/msgs/81995.html