Posted by pat c. on November 3, 2001, at 20:44:47
This link says that Nardil (Phenelzine) elevates GABA.
It also says that MAO-B is the primary MAO that is inhibited by Nardil to cause this elevation of GABA.
What I'm not sure about is that the article says that Deprenyl (MAO-B inhibitor) was used to prove this theory. Since Deprenyl reduced the GABA-elevating action of rats that were on Nardil, this proves MAO-B is the real MAO in play here? How can two MAOIs counteract each other? And why would that prove MAO-B is the primary MAO to be inhibted in order to raise GABA.
Thanks.
Pat
poster:pat c.
thread:83124
URL: http://www.dr-bob.org/babble/20011025/msgs/83124.html