Posted by SLS on November 8, 2001, at 7:46:09
In reply to Re: Moclobemide - GOOD results, posted by ben on November 7, 2001, at 23:38:43
> @ Scott and Sigolene:
>
> I wanted to hear from good results but you are scarey me ! So please do not post such bad reactions if it doesnt contribue to faithfullness.
Hi Ben.I guess I should have added a statement referring to the individual variability in how one reacts to these psychotropic medications (YMMV). Just about every antidepressant can cause depression to get worse for some people. I can't think of a single exception, so it would be difficult to justify excluding any one drug from consideration based on this potential adverse reaction. However, some drugs seem to do this more frequently than others. In my opinion, reboxetine is one such drug. As I see it, moclobemide helps much more often than it hurts. It also seems to help less often than it does help. Moclobemide has greatly lost its popularity and market share worldwide.
On the flip-side, just about every antidepressant is a miracle drug for some people. Again, I can't think of a single exception. Perhaps this will be true of moclobemide for you. I hope so.
Most people who do respond to moclobemide do so quickly, usually within the first week. However, it is the personality of this drug to lose effectiveness with time, often gradually. People tend to need dosage increases along the way, which often succeed in recapturing the antidepressant response. Some people do reach the upper limit of the dosage range, generally 1200 mg, without experiencing a stable antidepressant response.
These are the facts as I have come to know them. My sources include peer-reviewed medical journals, conversations with many researchers and clinicians, personal experience, and the descriptions by others of their personal experiences. I think it is important that people post this type of information (which may or may not be accurate) on Psycho-Babble. You may not find it anywhere else. I believe it is crucial that this board act as a clearinghouse of personal experiences, good and bad. In my opinion, this is the true value of this newsgroup.
A few things to remember:
1. Most people are here because they were not fortunate enough to fill their doctor's first prescription and live happily ever after.
2. That the biologies of these people are probably somewhat different from those who respond easily to treatment might yield a trend towards unusual negative reactions to medication.
3. People who have not had a negative reaction to a specific drug are less likely to post about their non-experiences. For every person who describes a negative reaction to a drug, there are probably many more who haven't.
4. People can be wrong about the information and opinions they post. Even doctors and Ph.D.s are capable of being wrong, so an appropriate amount of caution must be maintained when evaluating the validity of statements made by people who are not.
Without knowing the specifics of you situation, I cannot think of any reason for you not to try moclobemide. Moclobemide can and does work, and it usually produces very few, if any, side effects.
Good luck.
- Scott
poster:SLS
thread:83255
URL: http://www.dr-bob.org/babble/20011104/msgs/83512.html