Posted by Chocoholic on November 25, 2001, at 21:56:44
In reply to Re: Moclobemide, really works in just 1 week? » Chocoholic, posted by SLS on November 25, 2001, at 12:05:14
>Hi, Scott-
Here is a brief history--
I was diagnosed with Bipolar II about 5 years ago, at first by process of elimination. I have been through probably 20-30 different drugs in the last 9 years. When I was diagnosed I had been in the throes of a suicidal depression. First I started on Serzone, then added lamotrigine (one of my favorite meds of all time--I could make a great commercial for it!). The Serzone was only minorly helpful, but the lamotrigine cleared out some of the fog and let me think again. A year later,we substituted the moclobemide after someone at the FDA finally told me how to get it (I had researched it a couple of previous years). It really helped increase the quality of my life and functioning, and more and more over time. However, I still was cycling a lot and still getting some pretty awful (but not nearly as profound or long-lasting) depressions--it is all relative, I guess. So, this past year, I went to see Terence Ketter at Stanford and he gave me a huge list of ideas. So, I first added ziprasidone, then dropped moclobemide and added pramipexole (Mirapex). I am doing a lot better, in spite of some pretty heavy stressors in my life.I am still pissed about having this disorder, though and wish that the damn suffering would go to hell and never return!I don't have social anxiety, but my niece was working with Michael Liebowitz at Columbia while he was doing a study with moclobemide for social anxiety. I can ask her about the results if you are interested.
Now I have a question for you since you are so knowledgable about meds (I love reading your posts!). I want to get off Restoril--I've been on benzos for over 12 years. Supposedly the thought now is to switch people to Valium or Klonopin and titrate down from there because of the smaller possible increments and longer half lives. Only I get really depressed on long-acting benzos. And I guess I need to cut back by tenths--and I can't divide a capsule into tenths. So, do you think it would be feasible to just not take the drug one night every ten days and go down like that? Do you think it would be stable to pour out the powder and mix it in with liquid and drink 9/10 and do it that way? Any other ideas? Do you know of a pharmacy that might make Restoril in liquid form?
Chocoholic
Hi there, Chocoholic.
>
> > I took moclobemide for 3 years. I did get a quick response-can't remember if it was one week, but it was at least by two weeks. My response improved over time and I titrated up to 450 for my best response. More made me too agitated.
>
> Are you still taking moclobemide?
>
> If not, why did you stop taking it? How are you doing now?
>
> Do you have any social anxiety that moclobemide helped you with?
>
> Thanks.
>
>
> - Scott
poster:Chocoholic
thread:84453
URL: http://www.dr-bob.org/babble/20011123/msgs/85154.html