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Re: tiagabine and vigabatrin » Elizabeth

Posted by Emme on December 3, 2001, at 7:25:16

In reply to tiagabine and vigabatrin, posted by Elizabeth on December 1, 2001, at 15:33:29

Hi Elizabeth,

I tried gabitril along with taking neurontin and klonopin. I did a slow titration - it took me about 3.5 weeks or so to reach 12 mg. At 12 mg, it improved my mood and helped control my anxiety. But my body couldn't tolerate it at that dose - after a few days at 12 mg I started to have painful eyes that felt swollen, headaches, a sensation of pressure in my head, shakiness, and general cruddy feeling. My doctor ordered bloodwork to rule out some sort of infection and I promptly skipped a dose and resumed at 6 mg. As soon as I did that I felt better.

Until I hit the "helpful but intolerable" dose, it wasn't too bad to tolerate. I had less cognitive dulling than with trileptal. It seemed activating at the lower doses, but it's hard to say if it was the drug or if I was just having an especially anxious week or two.

I was taking it as a mood stabilizer. My doctor thinks I am somewhere in the bipolar spectrum, with depression my worst problem. I would definitely recommend giving it a whirl, perhaps in conjunction with something else. As I said, it helped my mood, though not to the point of complete remission of my depression. I am pretty sensitive to medicines, so you may be able to tolerate a therapeutic dose better than I was.
Good luck.

Emme

> Anyone have any experience with vigabatrin (Sabril) or tiagabine (Gabitril)? Why were you using the drug? What, if anything, did it help with? What side effects were there, if any? Do you have any other information about these drugs and their possible usefulness in the treatment of psych disorders?
>
> TIA.
>
> -elizabeth

 

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