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Re: GHB and XANAX » geno

Posted by Mr. Scott on January 20, 2002, at 16:45:07

In reply to GHB and XANAX, posted by geno on January 20, 2002, at 16:35:58

XANAX and GHB stimulate or intensify the effect of the brains major inhibitory neurotransmitter GABA (reduces activity of many other brain cells). Receptors adapt to the presence of the drug and therfore decrease in density. Then when you stop the drug the net effect is awhole lot more brain activity because it takes time for the downregulated GABA receptors to upregulate again. The resulting overactive brain accounts for the withdrawal syndrome and the potential for seizures. This is manageable however uncomfortable.

Scott


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