Posted by Rick on January 21, 2002, at 4:53:58
In reply to Re: Why no Olmifon/Adrafinil in US? » spike4848, posted by IsoM on January 20, 2002, at 22:16:01
> Perhaps they'll have an interest in marketing adrafinil in North America, or (& my pessimism is showing) will downplay adrafinil & push the more pricey modafinil (Provigil) which both Cephalon & Lafon markets now.
Seeing that I've finally found what works so well for me, I fully expect it to become unavailable in a matter of time.
> Given how lucrative the antidepressant market is (and adrafinil has an antidepressant indication in France, while modafinil doesn't), I would expect Cephalon to at least look into the possibility of marketing adrafinil here -- especially since it doesn't cause sexual dysfunction like the SSRI's.
BUT, in addition to the formidable "works-for-IsoM" hurdle, I see two more things adraf may have going against it:
-- I believe it's marketed in France mainly as an energizing AD for the elderly, which sounds pretty limiting, and
-- The need for liver-function tests. The FDA and the public are especially sensitized to this right now with the liver-failure problems that have hit some high profile drugs recently (especially Rezulin and Baycol, and to a lesser extent Serzone). The ambulance-chasers are having a field day.
Rick
poster:Rick
thread:90919
URL: http://www.dr-bob.org/babble/20020116/msgs/90956.html