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Re: Combinations Tricyclics for OCD » TSA West

Posted by spike4848 on January 22, 2002, at 0:23:55

In reply to Combinations Tricyclics for OCD » Shelley, posted by TSA West on January 21, 2002, at 13:02:11

> There is some evidence that suggests that clomipramine alone is not as effective as both clomipramine and a noradrenergic tricyclic (nortriptyline) for OCD:
>
> Journal of Clinical Pharmacy & Therapeutics, April 1998:
>

That is crap ... I have never heard a link between noradrenergic function and OCD .... I looked up that study and ...

1. These are the authors: Roozbeh Psychiatric Hospital, Tehran University of Medical Sciences, Iran. Not the most reputable sources.

2. There were only 30 patients in the trial

3. The authors admit this was a weak study and recommend "This study supports further investigation of the noradrenergic-serotonergic hypothesis in OCD." Further investigation.

I would need the full article to trash it completely. Be careful of what you read and what you recommend to others.

Spike


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