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An SSRI such as Zoloft would work better for you

Posted by 3 Beer Effect on February 8, 2002, at 19:24:28

In reply to MUST READ (deprenyl, klonopin, adderall, wellb..) , posted by Jason911 on February 8, 2002, at 4:01:05

DO NOT use l-deprenyl/eldepryl/(selegeline)/! If you have a short fuse/agitation or are easily angered a dopaminergic such as Eldepryl would be a bad choice for you. It will make your agitation & insomnia worse.

You sound like you would be much better off with an SSRI such as Zoloft with 0.5-1 mg of Klonopin in the morning to offset SSRI side effects & if you have insomnia- Klonopin 0.5 mg OR Ambien 5-10 mg at night. Zoloft even has some dopamine reuputake inhibition & so it is activating at 75 & 100mg & will get you out of bed ready to start the day. (The starting dose of 50 mg makes most people sleepy & is probably too low). I found out Zoloft gets rid of all social anxiety & depression & most fun of all, you can go up & talk to girls without even thinking about it, makes you an "instant mac!"- probably the best cure for social anxiety/shyness I have come across- for me, even better than Klonopin. Unfortunately I had to discontinue Zoloft since I turned out to have Bipolar disorder.

If you try the Zoloft I would absolutely avoid psychostimulants/dopaminergics all together. They are not physically addicting, but psychologically addicting meaning that once you start using them in order to study, it is almost impossible to study without them. Not only that but they decrease your social skills & often make you act like a nervous weirdo.

Eldepryl probably won't cure your depression & isn't used much as a dopaminergic antidepressant anymore because there are far superior & safer drugs such as Mirapex available for that. Eldepryl may or may not help you study, but Ritalin definitely will & results in much greater brain stimulation & focus. Since there are several different dopamine receptor subtypes different dopaminergic drugs will have different effects. Mirapex is a dopaminergic anti-depressant but won't help you study like Ritalin does.

Also, much of the research & info about eldepryl is funded by or comes from the overseas European companies that sell Eldepryl (selgeline) as a so called "smart drug" to US citizens through the mail & this "nootropic" smart drug research is pretty suspect & unreliable. Don't believe everything you read, especially on the internet. A more reliable source would be to read psychopharmacology/psychiatry books at Barnes & Noble although most don't talk about l-deprenyl because hardly anyone uses it. Be sure to read the PDR to find out about the side effects of Eldepryl & its dangerous interactions with anti-depessants before you really decide whether you want to take that stuff.

If you really do need a drug to help you study, you may have attention deficit disorder. Usually people with ADD respond to either Ritalin or Adderall but not both. I cannot study at all on Adderall but with Ritalin I feel like Albert Einstein. Ritalin has been found to be up to 70% effective for ADD, & as a psychostimulant I would bet anything that it vastly superior to deprenyl. Unlike other dopaminergenics, Ritalin usually won't increase your agitation or "short fuse", but allows you to focus on the task at hand with great concentration for about 3 & 1/2 hours- & then you are back to normal. You should take it 30-45 minutes before breakfast & lunch/or early afternoon, & then you can get all of your studying done and have no insomnia. My GPA at a academically rigorous university went from a 2.2 to a 3.0 on Ritalin. Additionally, a new & improved version of Ritalin called Focalin (which is the clinically active 'd-isomeer' of Ritalin) just came out that provides more brain stimulation with less peripheral side effects like anxiety or insomnia. Since Focalin is twice as strong as Ritalin, a 10 mg pill of Focalin is equal to a 20 mg pill of Ritalin. Both Ritalin & Focalin last about 3.5 hours.


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