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l-phenylalanine penetrates BBB better

Posted by 3 Beer Effect on February 16, 2002, at 2:59:26

In reply to DL-Phenylalanine - dose??, posted by NikkiT2 on February 14, 2002, at 15:51:43

>dl-phenylalanine may be somewhat helpful if you have chronic pain because it inhibits the breakdown of the body's natural painkillers.

Otherwise, for depression or as a stimulant, l-phenylalanine will work better because it crosses the blood brain barrier much easier. After a week or two at 1500 mg/morning, I started to notice a stimulant effect. (I have had success with Twinlab, but not w/ Bluebonnet or Country Life brands).

The normal dosages for L-phenylalanine or L-Tyrosine is 500 to 1500 gm per day. I have read books that recommend ridiculous amounts of these amino acids but no one knows if high dose aminos can cause long term effects/damage.

The problem with L-Tyrosine is that it does not cross the blood brain barrier & so is dependent & competes with other amino acids/proteins for uptake into the brain through a carrier that is already saturated by a normal diet. There is a form called n-acetyl-L-tyrosine that seems to be much bioavailable than L-tyrosine & would probably work better. N-acetyl-L-Tyrosine is relatively harder to find, but you could definitely find it on the internet. I am trying to find a good book/source on amino acid psychopharmacology but I have had a very difficult time finding unbiased info about amino acids online, or in bookstores. Most of the sites providing the amino acid research information also sell amino acids!

3 Beers.


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poster:3 Beer Effect thread:94137
URL: http://www.dr-bob.org/babble/20020215/msgs/94375.html