Posted by Charlotte on March 14, 2002, at 6:32:45
In reply to Re: Wellbutrin Ritalin » Charlotte, posted by TSA West on March 14, 2002, at 2:00:26
Thanks for your response and all the information. It seems like if I'm already taking Wellbutrin and Ritalin which both act like stimulants, would adding something like Modafinil be too much? I wonder if anyone has taken all of these drugs together.
> Some possible solutions:
>
> 1) Add a stimulating antidepressant like fluoxetine, reboxetine, or protriptyline.
>
> 2) Add a stimulant like Modafinil or Adrafinil.
>
> 3) Raise your dose to 450 mg of Wellbutrin.
>
> Fluoxetine and Energy Levels:
>
> "More than two thirds of patients with depression present with symptoms of fatigue, low energy, and listlessness. Because daytime sedation may be a concern in such patients, a "nonsedating" antidepressant should be considered. The authors examined the effects of fluoxetine on depression-related disturbances in energy. Data from seven double-blind, placebo-controlled clinical trials in 2,075 patients with major depression were retrospectively analyzed. The Hamilton Rating Scale for Depression (HAM-D) Retardation factor score (total of items 1, 7, 8, and 14) was used as the primary measure of energy improvement, whereas the HAM-D-17 total score was used to assess changes in overall depression. Elderly patients (aged 60 years and older) were included in the overall group and were also analyzed separately. In addition, a subgroup analysis was performed using the HAM-D Retardation factor score to categorize patients as having low (score < 8) or high (score >= 8) levels of retardation at baseline. Beginning at week 3, fluoxetine-treated patients experienced statistically significant reductions in their HAM-D Retardation factor score compared with placebo-treated patients. The reductions for the elderly subgroup were less than those for the overall population, but they were still statistically significant beginning at week 4. Patients in both the low and high baseline retardation groups improved significantly. HAM-D-17 total scores for fluoxetine-treated patients in all groups (total, elderly, high retardation, and low retardation) improved significantly compared with placebo-treated patients. These findings demonstrate that fluoxetine-treated patients experience an improvement in energy symptoms as their overall depression improves."
>
> --Journal of Clinical Psychopharmacology, December 2000. "Changes in Energy During Treatment of Depression: An Analysis of Fluoxetine in Double-Blind, Placebo-Controlled Trials"
>
> --------------------TSA West------------------
poster:Charlotte
thread:97835
URL: http://www.dr-bob.org/babble/20020313/msgs/97944.html