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Re: JOHNX2: wow, great explanation, more: » Janelle

Posted by JohnX2 on March 15, 2002, at 2:41:21

In reply to JOHNX2: wow, great explanation, more: » JohnX2, posted by Janelle on March 15, 2002, at 2:07:58

> Thank you a million for taking the time and having the patience to break down the reuptake, blocking situation for me in plain English. I basically got it except for one little part:
>
> Regarding the Serotonin aspect - you said that one of the serotonin receptors at Neuron B is the 5ht-2a receptor. This receptor does different things when serotonin is sitting on it. Some of those things aren't so nice. So we like to have a widget that sits on top of that 5ht-2a receptor at B and says "scat" to the serotonin -- my question dangling now is what does the 5ht-2a receptor do that is "not so nice" and what is the widget that is on top of that receptor at B that tells the Serotonin to go away?!
> Thanks ever so much, Janelle

The medicine sits on the receptor. It doesn't activate it though. Kind of like a key that was not cut for your door but fits in the lock.

I think mitch listed some things that are helped by blocking out this receptor (some side effects go away, like less sexual dysfunction).

Also some researchers believe that the receptor hinders the ability for genomic changes to take place that would enable a depression/anxiety to lift. There are many reasons why depression/anxiety may occur however. The brain is quite complex.

John



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URL: http://www.dr-bob.org/babble/20020313/msgs/98098.html