Posted by Elizabeth on March 26, 2002, at 21:36:45
In reply to Re: imipramine vs. desipramine-Elizabeth, posted by Lia Mason on March 23, 2002, at 19:19:14
> Thank you so much! This is exactly the info I've been after.
You're welcome. I'm glad to be of help whenever I can.
> I'm at 60 imipramine. I'm starting to get that floaty, dopey, sleepy feeling... I had it bad on 80 Pamelor so got off it. It's not just in the morning--it's constant. I wonder what the prognosis is... will the fog eventually clear? That's it for side effects.
Desipramine doesn't usually cause the tired/dizzy feelings that people often get on TCAs. It tends to be activating, if anything.
Oh, one thing you should probably consider if you've had a hard time tolerating TCAs: some people don't metabolize them very well, so the drugs build up in their bodies. This happened to me which is why I stopped taking desipramine. You can have your serum level tested; safe therapeutic ranges have been determined for imipramine, desipramine, and nortriptyline (maybe amitriptyline and/or clomipramine, not sure about those).
> Your info interests me very much (re: NE versus serotonin action).
I'm not sure it really matters that much, but I'm glad you're interested. :-)
> Prozac came on the market and I was switched to that with marvelous antidepressant results and bad side effects. So... I'm trying to go back to the tricyclics for less sexual dysfunction.
Desipramine wouldn't be expected to cause sexual problems to nearly the extent that Prozac does, but on the other hand, because they don't work in the same way, desipramine might not work for the same people for whom Prozac works.
Well, anyway, whatever you try next, I hope you find something that works for you sooner or later (preferably sooner).
best,
-elizabeth
poster:Elizabeth
thread:99075
URL: http://www.dr-bob.org/babble/20020322/msgs/100417.html