Posted by SLS on March 23, 2002, at 9:12:26
In reply to Re: Article on treatment resistant depression, posted by OldSchool on March 22, 2002, at 21:29:31
Hi folks.
> I wouldnt believe what you read about nomifensine being an ineffective antidepressant. It was one of the best ADs ever fielded from things Ive read. Certainly as good as a TCA and without the anti-cholinergic side effects.
Baron Shopsin (M.D.) considered nomifensine to be, in his words, shit. I had to plead with him to allow me to try it when it was marketed briefly as Merital. I responded to it robustly, but only for two or three days after a two-week latency. It was the only time he got to see me well.
I know of several people for whom nomifensine was the only drug that ever worked for them. Of course, this is also true of just about every other antidepressant. It seems like a sin to have had nomifensine yanked away from these people.
My knowledge of nomifensine is limited to what had appeared in the medical literature through the mid 1980s. I would be reluctant to attach to it hyperbole. However, I think it represents a unique therapeutic tool that I wish were still available. I would have liked to combine it with an MAOI.
- Scott
poster:SLS
thread:98605
URL: http://www.dr-bob.org/babble/20020322/msgs/99629.html