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Treatment Resistant Depression Parnate vs. Lithiu

Posted by M in Boston on April 2, 2002, at 12:24:54

I have treatment resistant depression that has been defined as atypical and reactive with a high degree of rejection sensitivity. Over many years I have tried more than 10 anti-depressants (including a range of SSRIs and Tricyclics - none with any significant success. My condition has worsened lately, due to a number of circumstances and reaction to an ended relationship, etc. My psychiatrist has reccommended for some time that I try an MAOI, but, having high blood pressure, I have been afraid of the apparently unpredictable and sometimes deadly potential for a hypertensive crisis, and the anxiety produced as a result. Another alternative that was suggested was to try lithium (about which I know little, particularly its efficacy in atypical reactive depression. Does anyone have any thoughts on the pros and cons of each, or which order of trial between the two makes sense?

Thanks so very much for your help.


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poster:M in Boston thread:101480
URL: http://www.dr-bob.org/babble/20020402/msgs/101480.html