Posted by JohnX2 on April 4, 2002, at 16:58:26
In reply to This is starting to scare me.., posted by Ritch on April 3, 2002, at 0:45:51
Mitch,I don't know what to say.
I came across the concept of pathological laughing and crying in the context of the "pseudobulbar affect" in ALS and MS.
Supposedly this is also related to some interactions in the frontal lobe, although I don't know all the nitty gritty details.I did find one medicine that was in clinical trials to treat this phenomina, but I don't know if it would help "gelastic epilepsy". This is a new one for me.
The medicine i was looking at was Neurodex. (Maybe you've seen some posts I've made on it).
http://www.avanir.com/product/product.php?ID=3
I read through some of your links swiftly, where did you find information that dexedrine helps with "gelastic epilepsy" (or was this just your own observation). ?
PS, I once did an EEG and it turned up nada.
I wonder if Lamictal would help you (given its activity at the nmda receptor)? (SWAG)
John
> John,
>
> I just casually mentioned the gelastic epilepsy thing and the dexedrine. I saw something somewhere in my memory that made me think of it. But I just did some searching about and drug up a lot of creepy crap that sounds a lot like some of my symptoms. Most especially, some of the things relating to autonomic instability (blood pressure, basal temperature, heartrate, and GI symptoms) and the "flushing" and laughing response to Luvox. When the neuro I saw once mentioned something about frontal lobe problems-it was related to some gastrointestinal problems I was having with Prozac at the time. It felt like my esophagus (just below my ribcage) was "pushing out"-like I had a rod shoved through there to my spine-like my guts were all going to fly out if I didn't hold them in. I was also having some nightime "sub-hallucinations" on the Prozac. Here is some of the links I found that are freaking me out (what do you think?):
>
> http://mentalhealth.com/fr30.html
> http://www.epub.org.br/cm/n13/mente/laughter/page5.html
> http://www.john-libbey-eurotext.fr/articles/epd/1/4/221-8/
> http://www.geocities.com/hhugs2001/infoabouthh.htm
> http://www.epilepsy.org/ctf/gelastic.html
> http://murdoch.rch.unimelb.edu.au/pages/clinical/neurosciences/projects.html
> http://archinte.ama-assn.org/issues/v159n17/ffull/ilt0999-5.html
poster:JohnX2
thread:100774
URL: http://www.dr-bob.org/babble/20020402/msgs/101836.html