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Re: Lupron reactions/gonadotropins » judy1

Posted by Elayne on April 7, 2002, at 13:09:51

In reply to Re: Lupron reactions » Elayne, posted by judy1 on April 6, 2002, at 14:51:02

> Hi,
> In an IVF cycle lupron prevents premature ovulation- so fertility docs use it for a period of time to suppress estrogen and androgen production, then come in with gonadotropins to stimulate the ovaries for maximum # of eggs. It's also used in women with severe endometriosis. Hope that helps- judy

Judy,
I'm wondering if your depression developed after gonadotropin stimulation or in response to the Lupron itself. What I'm trying to get straight is whether Lupron itself is the bad actor.

If it's used alone (as in endometriosis or to shrink fibroids, say), it basically induces menopause. It's as close as you can come to surgical oophorectomy without having surgery. You can then add back estrogen at the low levels used in hormone replacement therapy. If a woman does well, then she might do well after surgical oophorectomy. If she doesn't, she can stop the treatment. But if she has an oophorectomy and doesn't do well, or has problems tolerating exogenous estrogen, the situation is a lot trickier. Does that make sense?
Elayne


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poster:Elayne thread:101606
URL: http://www.dr-bob.org/babble/20020402/msgs/102259.html