Posted by James on April 14, 2002, at 11:02:26
In reply to Re: Risperdal » James, posted by TSA West on April 14, 2002, at 6:52:40
> Here is the basis for Risperdal's use in bipolar disorder. I sincerely hope that you make a complete recovery on Risperdal and Gabitril:
>
> J Clin Psychopharm, April 1998:
> RISPERIDONE
> "This encouraged us to conduct an open trial on the efficacy and safety of risperidone in the treatment of 10 patients with rapid cycling bipolar disorder who were refractory to lithium carbonate, carbamazepine, and valproate... Patients fulfilling Research Diagnostic Criteria for bipolar I or bipolar II disorder with DSM-IV rapid cycling were included... Risperidone was administered orally twice a day in morning and evening dosages, starting from 1 mg twice a day. This dosage was subsequently modified depending on clinical status and side effects...
> Eight of the 10 patients improved after the implementation of risperidone. Two patients dropped out because of agitation and noncompliance, respectively. The number of episodes within 6 months after baseline was significantly lower than before baseline.
> The results of this study suggest that risperidone could have mood-stabilizing effects and be a good choice in the treatment of refractory rapid cycling bipolar disorder."
Thank you very much for your all of your responses. I didn't know that Risperdal is used to treat bipolar at all. The choice of Risperdal over others might be because of my previous experience with Zyprexa, which was helping at the time, but also raised my liver enzymes to a dangerous level, so I was forcved to discontinue its use. Thanks a lot both of you.
--James
poster:James
thread:103003
URL: http://www.dr-bob.org/babble/20020408/msgs/103041.html