Posted by djmmm on April 16, 2002, at 9:29:36
In reply to Re: Selegiline MAOI patch rejected by FDA » AnnieDonia, posted by IsoM on April 16, 2002, at 1:09:12
> Annie, the way pharmaceutical companies are set up & operate is the same with just about everything else in this corrupt world - the bottom line is 'will the profit be large enough'?
I just don't agree with this...I bet If you were to take a poll of both currently depressed people not responding on meds, and those who are on meds and consider themself recovering or responding, you would find a great majority of *all* of them willing to try this patch.I take an oral MAOI, and consider myself cured, I would be willing to try the Selegiline patch in a second...*IF* it was as effective as the early Bodkin studies show.
The fact remains, We are disparate for new treatment options, the drug co's know that, and the FDA knows that. The FDA is not the corrupt superpower it is made out to be.
If there is any concern about letting a drug on the market, you should be concerned about drugs that are released that truely perform poorly in tests, or have undisclosed dangerous side-effects. This information is held back by the drug co's not the FDA.
All we can do is wait until Somerset Pharm. tweaks their research methods, so they can present an adaquate statistical difference (vs placebo).
If several studies can show St johns Wort a "safe and effective antidepressant" Somerset should have no problem
> The fact the Selegiline patch works very well for some isn't reason enough for them. I guess they figure there's not a big enough profit margin in it to proceed. One thing that's hopeful is it may be picked up by another company instead.
>
> Another post mentioned a drug study being done on a substance P antagonist labelled MK-869. Merck jumped on it & got to stage III (I think) testing before they realised that people were responding just as well to the placebo & dropped it. They didn't take other factors into consideration &, in my opinion, stopped it prematurely. Some other companies such as Pfizer & Eli Lilly have taken it up instead & are working further with it.
>
> Maybe the same will happen with the Selegiline patch. There's bound to be a few researchers involved who'll note that it did work wonderfully with some & spread the idea or cross over to the competition & they'll decide they don't have a big new winner & will go at it. I really wouldn't be surprised to see it come up with another company. The competition to come up with new or improved ADs is intense & very political too.
poster:djmmm
thread:100963
URL: http://www.dr-bob.org/babble/20020416/msgs/103219.html