Posted by JohnX2 on April 16, 2002, at 23:56:54
In reply to Re: ZOLOFT Increase, more anxiety? 3 beers, posted by geno on April 16, 2002, at 19:14:12
> John, do you mean 1mg 2x a day. How many hours apart. I feel it last only 10 for me. The latter few i could feel the anxiety creeping up. How about this:
> Remeron 30mg at bed
> Ditch desipramine
> 50mg zoloft 8am
> 1mg klonopin 8am
> 1mg klonopin 4pm
>
> What do you think.
> geno
Well, I guess that looks like a good plan.I think if you dose the Klonopin 2x a day, after a while it will build up in your system so that you don't feel the ups-and-downs. I know what you mean about the 10 hr affect for a 1x dosing...this is what I felt. But if I dose it 2x a day, it seems to build up to a more steady state (probably has to do with how the medicine's 1/2 life and how the repeated dosing is decaying in your body). I would just give it a go. You may need a 3x a day dosing. Maybe 0.5 mg morn, 0.5 mg afternoon, 1 mg night. Something should work out.
Is your pdoc reluctant to let you take the Klonopin 1 mg 2x a day?
I don't know much about Desipramine, so I wouldn't want to predict interactions there. I just know that Zoloft can be remarkedly stimulating. If you feel that Zoloft is stimulating, then ditching Desiramine might not be a bad idea (going by the less medicine is better approach than more medicines when possible)...
Take Care,
John
poster:JohnX2
thread:103249
URL: http://www.dr-bob.org/babble/20020416/msgs/103300.html