Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: SSRI's - why they loose their effect...

Posted by crepuscular on April 24, 2002, at 10:50:56

In reply to Re: SSRI's - why they loose their effect..., posted by tex1 on April 24, 2002, at 3:03:48

interesting. i've come to the opposite conclusion.

i see the effect of AD's as not specific to the transmitter system affected, nor the amount present in the synapse, nor even the direction of inhibition (+ serotonin, - serotonin). rather, i see the brain's response to these agents, and the subsequent gene products/neurotrophic factors created as the final common pathway of the effect.

how else might we explain antidepressants that work by *reducing* serotonin? or the myriad of transmitter systems that are all tweakable as potential AD action sites? same goes for ECT.

i'm not a giant fan of using the specificity of modern AD's as explaining depression as "low serotonin" though in some people, this is indeed the case...


Share
Tweet  

Thread

 

Post a new follow-up

Your message only Include above post


Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.

 

Start a new thread

 
Google
dr-bob.org www
Search options and examples
[amazon] for
in

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:crepuscular thread:103897
URL: http://www.dr-bob.org/babble/20020416/msgs/103989.html