Posted by jay on April 30, 2002, at 19:23:59
In reply to ZOLOFT{{{{{{ TO 3 BEERS, posted by Geno on April 30, 2002, at 16:27:45
Geno, I was on Zoloft for about two years, so I hope I can help. I honestly think that in your situation, the Zoloft+benzo (whichever one) is *the* most powerful combination. I would say up the benzo a bit more, and attempt between 75-100 mg's on the Zoloft. Just make sure you go VERY slow. I must emphasize though, keep the benzo dose high, as that caps the anxiety Zoloft causes. When you get the right mix, I found it excellent, but it took a very particular mix...it may be a bit different for you, so toy around with the mix. BTW...Benzo's work very differently then the mood stabalizers on GABA. So, no, Neurontin et al does not have near the same effect as benzos.Trust me, I have spent many years toying with benzos and a.d's, tried all the other crap, and these two (a.d. + benzo) still treat most psychiatric conditions very well. (All range of depressive and anxiety disorders.)
Good luck
Jay
P.S. Don't count on Zoloft's dopamine properties too much. Even if it does bind fairly strong to dopamine at high doses, the excessive serotonin stimulation will lower it's dopamine properties greatly.
> Ok, what i gather from ghb, is when you ingest it, it temporarily raises seratonin levels. Then when it wears off, it returns to normal, unlike alcohol, it doesnt deplete it. It also creates dopamine, due to rebound effect. also gaba enhancement, via gaba b. You are right about baclofen, a gaba b enhancer. GHB for unknow reason, creates a substance called oxytocin in the brain, which is responsible for social states. Its funny how dose dependand g is. Just the right dose, makes one feel great. Just a litle more, good night. this is due to dopamine suppression, and gaba.
>
> Now my question to you is. Iv been on zoloft 50mg for 2 weeks. Also been taking that small .25 xanax with it. Iv been steady, not sleepy, nor anxious. No mood improvement, only slighty, VERY slightly more talkative. Then i take .5mg to 1mg of klonopin at noon which takes me into the night, then remeron at bedtime 11pm.
>
> Should i up the zoloft to 75mg and take .5mg of xanax? i know that ittybitty dose of .25 wont help. When you mean activaton, do you mean like stimulated feeling, due to the dopamine reuptake. I have a great book, called psychotropic drugs. it breaks down the drugs and receptors. IT SHOWS, welbutrin has dopamine reptake THE SAME score as zoloft at high doses. MMMM
>
> Also, did your sex drive improve at 75-100mg doses? DId you just start at 75 when you started?
>
> geno
poster:jay
thread:104553
URL: http://www.dr-bob.org/babble/20020425/msgs/104575.html