Posted by JahL on May 3, 2002, at 20:19:33
In reply to Re: 'Sulpiride' and anxiety » JahL, posted by Ken on May 3, 2002, at 17:58:13
> Since sulpiride (like amisulpride) has opposite effects on DA neurotransmission at "low" (dopaminergic) doses versus the higher (anti-dopaminergic) dosages... Can you tell us what dosage of sulpiride you take to achieve the above results? 50 mg? 100 mg? More? Less?
Hi Ken. 150mg is about optimum for me; there are no further benefits beyond that point and sedation starts to kick in. This dose seems to be fairly standard (if a little on the low side) going by what pdocs have told me.
Hi John. Contrary to the claims of an earlier poster, both Amisulpride & Sulpiride most certainly do possess anxiolytic properties; if they didn't they wouldn't be regularly prescribed for anxiety (& particularly s. phobia) by, amongst others, the staff of the Maudsley hospital (the UK's pre-eminent, or at least most famous, psych unit.). I've seen a few pdocs & profs there over the years and all of them, w/o exception, viewed both drugs as 'effective' (like all drugs, only for certain individuals) second or third line agents for anxiety, and not depression (they are used for that purpose on the Continent but the consensus here seems to be that the AD effect, when apparent, is fairly mild).
I was first prescribed Sulpiride (indication: anxiety) by a provincial pdoc so, whilst it may not be a commonly used drug, its anxiolytic properties are recognised beyond the confines of teaching hospitals.
Regards,
J.
poster:JahL
thread:104842
URL: http://www.dr-bob.org/babble/20020503/msgs/104981.html