Posted by Iago Camboa on June 6, 2002, at 14:09:50
In reply to Re: dopamine to noradrenaline » turalizz, posted by Ritch on June 6, 2002, at 10:15:37
> > Hi,
> >
> > Selegiline, in the MAO-B selective dose range would increase the dopamine levels, and since dopamine is the precursor to noradrenaline, selegiline would also effect noradrenergic transmission indirectly. Am I wrong?
> >
> > cem
>
> Yes, it would. Perhaps a more important player is one of selegiline's metabolites-methamphetamine. That one definitely releases noradrenaline and blocks its reuptake.
>
> MitchUnfortunately both amphetamine and methamphetamine (which are indeed selegiline's metabolites) are produced in amounts far too tiny to have ANY practical value whatsoever (either therapeutic or recreational).
Iago
poster:Iago Camboa
thread:108919
URL: http://www.dr-bob.org/babble/20020602/msgs/108966.html