Million dollar answer! Everyone should read this.

Posted by Shawn. T. on July 12, 2002, at 1:52:55

In reply to Remeron Question for Shawn. T., posted by fachad on July 11, 2002, at 23:29:34

I think I give new meaning to psychosomatic addict insane :) This got me so interested I forgot to take my Remeron! People gaining weight on Remeron may be responding to its effects on cortisol, as I believe the following should illustrate nicely.
By the way, I have reason to believe the following may be ways to tests for various diseases. I also believe that studies should be conducted on the substances which break down each of these substances. I am going to see if my local hospital can test me for cholesterol and its derivatives. I believe my levels should be normalized judging on how good I feel. My sister with fibromyalgia is also going to be getting tested, but she doesn't know it yet. Actually I'm going to convince my entire family.
I have read that Remeron increases cholesterol levels, that very much makes sense to me(see my last link for a good diagram on all of this).
Note that DHEA-S information can be found in the anxiety disorder study. You can also find out why benzodiazepines work!!! This has major implications for antidepressant mechanisms and the role of 5-HT2 receptors! Also note that caffeine inhances cortisol release, which may explain why it is a common ingredient in many diet aids. This also ties into why Phen-Fen is dangerous! If I could combine all of this with information on levels of intermediary breakdown substances, I could further explain all of these afflictions. Note that this explains who and who will not benefit from DHEA dietary supplements. This also seems to imply that someone with chronic fatigue syndrome should not take Remeron! I'll let you guys make some more logical connections with all of this; I'll add more as I come up with them. It is certainly a very well developed model of abnormalities in the HPA axis. I have reason to believe that schizophrenics do not have an altered HPA axis unless of course they have comorbid afflictions with one of the disorders listed.
Anxiety Disorders: High cortisol, DHEA
Depression: High cortisol and Low DHEA-S
Chronic Fatigue: Low cortisol, DHEA, DHEA-S
Depression: High cortisol and Low DHEA and/or DHEA-S
Fibromyalgia: High cortisol and Low DHEA-S (and/or DHEA???), androgens
=>A note on this... perhaps some chronically obese patients are unable to properly breakdown cholesterol? Perhaps anorexics break it down too easily? See the following. I would guess that patients with bulimia have lower levels of 17beta-estradiol than those with anorexia.
Anorexia: High 3alpha, 5alpha-THP, DHEA, DHEA-S, cortisol and Low 17beta-estradiol, testosterone
Bulimia: High 3alpha, 5alpha-THP, DHEA, DHEA-S, cortisol and Low 17beta-estradiol.
AIDS w/ symptoms: HIV+ and High cortisol, testosterone, estrone and Low DHEA, DHEA-S, androgens (Advanced AIDS sees increased levels of estradiol)
AIDS w/o symptoms: HIV+ and High cortisol, estrone, androgens and Low DHEA, DHEA-S (I believe these patients may exhibit low testosterone)
Furthermore, individuals with low levels of DHEA and high levels of testosterone (DHEA is a precursor to testosterone and androgens) are at a higher risk to contract HIV.
"Initiating protease inhibitor combination therapy was associated with an increase in DHEAS over 6 months (that is good!)"
On anxiety disorders:
http://www4.infotrieve.com/search/databases/detailsNew.asp?artID=9223436
On chronic fatigue:
http://www4.infotrieve.com/search/databases/detailsNew.asp?artID=9899382
and
http://www4.infotrieve.com/search/databases/detailsNew.asp?artID=29938079
On depression:
http://www4.infotrieve.com/search/databases/detailsNew.asp?artID=10889076
On Fibromyalgia:
http://www4.infotrieve.com/search/databases/detailsNew.asp?artID=4982488
On Anorexia & Bulimia:
http://www4.infotrieve.com/search/databases/detailsNew.asp?artID=16264486
On AIDS:
http://www4.infotrieve.com/search/databases/detailsNew.asp?artID=29503255
and
http://www.naples.net/~nfn03605/dheaaids.htm
See http://www.psychosomaticmedicine.org/content/vol61/issue5/images/large/G0465F1.jpeg
For the link between cholesterol and DHEA.
And finally DHEA-S levels linked to cardiovascular disease. This also helps to explain increased rates of major depressive episodes in the elderly.
http://www4.infotrieve.com/search/databases/detailsNew.asp?artID=19458812

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Remeron Question for Shawn. T. fachad 7/11/02
Re: Remeron Question for Shawn. T. cybercafe 7/12/02
Million dollar answer! Everyone should read this. Shawn. T. 7/12/02
Re: Million dollar answer! Everyone should read t » Shawn. T. Elroy 5/25/05

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