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Re: Depakote, Lamictal Prozac??? » Geezer

Posted by Ritch on July 23, 2002, at 13:37:36

In reply to Re: Depakote, Lamictal Prozac??? » Ritch, posted by Geezer on July 23, 2002, at 12:15:57

> Hi Mitch,
>
> Thank you for the information about this complex situation. Its not a real heavy mix but difficult for me to figure out when I am sick and confused. I was not aware of the influence of various blood levels by using Lam. and Dep. at the same time, only aware of the slow titration of Lam. to avoid rash.
>
> In answer to your question about depressive symptoms. They are atypical, reactive, hypersomnia, limb ladency, etc. (no agitation or anxiety). Parnate was offered by new pdoc (probaby the right way to go) but he is not up to speed on Lam. and Dep. togeather. I wanted to try Prozac again because it had been so successful in the past, was not attracted to Parnate due to food restrictions (though no big deal), start-up side effects, and multiply daily dosing. Have to due a 6 to 8 week wash out now on the Prozac before going to Parnate (if I decide to do that). I DCed the Prozac this AM....just could not stand the dizziness and nausia any longer. Things seem slightly improved. I had a full trial on Zoloft (up to 200mg. for several weeks) about 8 months ago while on Dep. only.....no relief. I am about fed up with SSRIs. What would you think about a direct crossover to Wellbutrin? I tried it a year ago (prior to Dep.-never pushed the dose too high and not sure I took it long enough).
>
> Thanks for your help! Don't worry about comments - I clear everything with pdoc, he is pretty open and willing to work with me. Respect your opinion, follow your posts on the board, and I believe we have had correspondence in the past.
>
> Best regards
>
> Geezer


Hi,

What you might want to do in the future.. is have a blood draw for *both* lamotrigine and Depakote (the exact same post dosing times, etc.), whenever you change medications (after a week or two), just to see if they are undulating around due to other unrelated med changes. Polypharmacy is a pain, huh? :) Just an idea here.. but I could *never* tolerate "therapeutic" doses of antidepressants of any kind. Just my own personal experience, but, smaller doses seem to work better (they are also less destabilizing). You could try the Wellbutrin and see how it goes. If you don't get agitated and anxious, you might find it helpful. I can't take much of it, however (too agitating and sleep disruptive). Since you stopped the Prozac, it will be a gentle, slow washout. You could try WB right off while the Prozac is washing out and see. If that bombs, you will at least have the Prozac out of your system, and the WB will wash out quicker than most others if you try the Parnate later on.

good luck,

Mitch


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poster:Ritch thread:113330
URL: http://www.dr-bob.org/babble/20020718/msgs/113417.html