Posted by psycHarvard on September 6, 2002, at 22:52:01
In reply to Re: Fewer s/e with Lexapro - where's the evidence?, posted by Phil on September 6, 2002, at 8:27:35
> May I ask what your involvement was in the studies?
No personal involvement in the studies... I talk all over the U.S. and Europe on behalf of most of the pharma... the information that I post is not my opinion... in a way it is but I am working off what I have seen in the majority of pats and from all the information I have seen in learning extensively the products that I have talked about.
> We're uninformed about Lexapro because of a lack of subjective information.
> I'd like the answer to three questions, if you will. Sexual SE, less or more than Celexa- -That depends on if you look in the P.I. for Lexapro and Celexa and compare them.... Lexapro rates are slightly higher we are talking about rates that are not even clinically important.
Now the reason for this is simple.... 5HT will always cause a little sexual dysfunction... in the studies conducted on Celexa... which was a few years ago now pats were not as forth coming as they are now in admitting sex dys....as they are now... now you can have a hard time telling what this really means in the end.... the Lexapro P.I. states sex dys as 9% for delayed ejaculation.... not always a bad thing.... the rate is very low..... you should always look for AEs under 10%.... anything under this is acceptable... the other rates for Lexapro as far as I know is impotence 3% and for females decreased libido 2% and anorgasmia 2%..... so what I am saying is that the real studies are the ones that the pats who are starting on Lexapro will talk about..... but for the majority of the population they will experience rates similar to these... there will always be pats that cannot tolerate even the best of any med.... and no one knows why...
Weight gain, less or more than Celexa-
Weight gain...weight loss in Lexapro... comparable to Celexa... and they are both comparable to placebo in regards to that also.
-Emotional blunting and apathy, less or more than Celexa... this is not so easily to measure as you know depression like many of the disorders are very subjective in measurement.... so that is something that I cannot comment on for the majority of people... it really is a case by case feeling emitted by the pat... as far as I know no studies have been conducted in this area.
> I'll be switching to Lexapro from Celexa early next week. Any info appreciated.
You can start Lexapro therapy the next day after stopping Celexa... 10mg is what they should start you on....My time is very limited and I am not always able to get to a computer... but when I can I will answer your questions.
poster:psycHarvard
thread:109458
URL: http://www.dr-bob.org/babble/20020906/msgs/119128.html