Posted by dr dave on October 10, 2002, at 12:06:48
In reply to Lexapro news » dr. dave, posted by Anyuser on October 10, 2002, at 8:41:01
It sounds like good news. I don't have comparative data to hand to know whether this
represents a significant improvement over other antidepressants though.As to whether it's good science, that's the $64,000 dollar question, and we have no way of knowing without seeing the details of the actual study. If the study is flawed, the information may be worthless. If it's a sound study, then it's potentially very useful.
What we've got is a marketing claim which may or may not be true. We need to see the details before we can accept it. That's only common sense, in my view.
> From docguide.com:
>
> "Escitalopram 10 to 20 mg/day for treatment of moderately to severely depressed subjects showed ongoing and increasing efficacy throughout a 12-month, open-label study conducted at 97 sites.
>
> "The study's findings were reported at the 15th Congress of the European College of Neuropsychopharmacology (ECNP).
>
> "'The remission rate among the subjects continuing in the open-label study reached 86 percent by week 52,' said lead investigator Alan Wade, MBChB, director at the CPS Clinical Research Centre, in Glasgow, United Kingdom. 'This long-term, primary care-based data begins to fill out the picture of escitalopram as a drug that raises the bar of expectations for effective and tolerable treatment of this group of patients.'"
>
> This study was funded by Lundbeck.
>
> Do you think this is news? Good science?
>
> I wish we could see the data re clinical experience, but it is not reported.
poster:dr dave
thread:109458
URL: http://www.dr-bob.org/babble/20021006/msgs/123074.html