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Re: P.S. Selegiline and the Pill » jackstraw232

Posted by Rick on October 17, 2002, at 18:47:13

In reply to Re: P.S. Selegiline and the Pill, posted by jackstraw232 on October 17, 2002, at 13:30:42

> The smell is quite pungent; I would say of sulphur.

Funny, I never noticed the smell. (We ARE talking about selegiline here, right? Or did this refer to adrafinil?)


>Adrafinil actually has a half life of one hour; it breaks down very quickly and I assume is excreted in urine. Do you have any idea to what degree this substance is detectable in urinanaysis? What if you got drug tested? Would adrafinil be a substance that, say, the police or my employer would be looking for in the case I was suspected of drug abuse or randomly subjected to urine toxicology?

Whether it's detectable in urine or not, I don't think there's anything about adrafilinil or its metabolites that would put up a red flag in drug tests. Selegiline, of course, is a different story, since one of its metabolites is methamphetamine.

>And, how much damage are adrafinil users risking to the liver?

I'm not sure about the extent of liver risk, but if the drug was very dangerous in this regard then France's equivalent of the FDA would not allow doctors there to prescribe it. Quarterly liver function tests are recommended with adrafinil, to catch any toxicity and stop the med before it does any damage. If you're on almost any psychotropic it's a good idea to have liver function tests at least twice a year, especially if you're taking multiple liver-metabolized drugs (psychotropic or otherwise).


Rick


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URL: http://www.dr-bob.org/babble/20021012/msgs/124055.html